Anti-FoxK1 (G698) Antibody

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Transcriptional regulator that binds to the upstream enhancer region (CCAC box) of myoglobin gene (By similarity) . Important regulatory factor of the myogenic progenitor cell population (By similarity) . Involved in the cell cycle process, promotes proliferation by repressing Foxo4 transcriptional activity and the cyclin-dependent kinase inhibitor, p21CIP, in the myogenic progenitor cells (By similarity) . Represses myogenic differentiation by inhibiting MEFC acitivity (By similarity) . Has a role in remodeling processes of adult muscles that occur in response to physiological stimuli (By similarity) . Required to correct temporal orchestration of molecular and cellular events necessary for muscle repair (By similarity) . Positively regulates Wnt/beta-catenin signaling by translocating DVL into the nucleus (PubMed:25805136) . Reduces virus replication, probably by binding the interferon stimulated response element (ISRE) to promote antiviral gene expression (PubMed:25852164) .