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Anti-TBL1X Antibody

Boster Bio Anti-TBL1X Antibody catalog # A07014-1. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

F-box-like/WD repeat-containing protein TBL1X; SMAP55; Transducin beta-like protein 1X; Transducin-beta-like protein 1, X-linked; TBL1X; TBL1;

Gene Name

TBL1X

UniProt

O60907

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide of human TBL1X (NP_005638.1) .

Clonality

Polyclonal

Tissue Specificity

Ubiquitous.

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Dilution

WB: 1:500-1:2000

Form

Liquid

Function

F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units (PubMed:14980219) . Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of corepressor complexes that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of transcription repressor complexes, thereby allowing cofactor exchange (PubMed:21240272) .

Molecular Weight

62496 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

F-box-like/WD repeat-containing protein TBL1X

Subcellular Location

Nucleus . Colocalized with MECP2 to the heterochromatin foci.

Protein Name

F-box-like/WD repeat-containing protein TBL1X

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