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Anti-SEC24D Antibody

Boster Bio Anti-SEC24D Antibody catalog # A06985. Tested in WB, IF applications. This antibody reacts with Human.

Product Specifications

Synonyms

Protein transport protein Sec24D ; SEC24-related protein D; SEC24D

Gene Name

SEC24D

UniProt

O94855

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant protein of human SEC24D

Clonality

Polyclonal

Tissue Specificity

Ubiquitously expressed, with higher amounts in placenta, pancreas, heart and liver.

Applications

WB, IF

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Form

Liquid

Function

Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER) . The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex (PubMed:17499046, PubMed:20427317, PubMed:18843296) . Plays a central role in cargo selection within the COPII complex and together with SEC24C may have a different specificity compared to SEC24A and SEC24B (PubMed:17499046, PubMed:20427317, PubMed:18843296) . May more specifically package GPI-anchored proteins through the cargo receptor TMED10 (PubMed:20427317) . May also be specific for IxM motif-containing cargos like the SNAREs GOSR2 and STX5 (PubMed:18843296) .

Molecular Weight

113010 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

Protein transport protein Sec24D

Subcellular Location

Cytoplasmic vesicle, COPII-coated vesicle membrane

Protein Name

Protein transport protein Sec24D

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