What is the catalog number for Anti-Lrwd1 Antibody?

The catalog number for Anti-Lrwd1 Antibody is A06834.

What sizes are available for Anti-Lrwd1 Antibody?

Anti-Lrwd1 Antibody is available in the following size(s): 100 µL.

Is Anti-Lrwd1 Antibody in stock?

Anti-Lrwd1 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-Lrwd1 Antibody?

The safety data sheet for Anti-Lrwd1 Antibody is available here: https://www.bosterbio.com/msds?sku=A06834.

Anti-Lrwd1 Antibody

Boster Bio Anti-Lrwd1 Antibody catalog # A06834. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Leucine-rich repeat and WD repeat-containing protein 1; Centromere protein 33; CENP-33; Origin recognition complex-associated protein; ORC-associated protein; ORCA; LRWD1; CENP-33

Gene Name

LRWD1

UniProt

Q9UFC0

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide of human Lrwd1 (NP_690852.1) .

Clonality

Polyclonal

Tissue Specificity

Testis-specific. Drastically down-regulated in testis from patients with Sertoli cell-only syndrome (SCOS) .

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Dilution

WB: 1:200-1:2000

Form

Liquid

Function

Required for G1/S transition. Recruits and stabilizes the origin recognition complex (ORC) onto chromatin during G1 to establish pre-replication complex (preRC) and to heterochromatic sites in post-replicated cells. Binds a combination of DNA and histone methylation repressive marks on heterochromatin. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3 in a cooperative manner with DNA methylation. Required for silencing of major satellite repeats. May be important ORC2, ORC3 and ORC4 stability.