Anti-DNAJC2 Antibody
Boster Bio Anti-DNAJC2 Antibody catalog # A06788. Tested in WB applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
DnaJ homolog subfamily C member 2; M-phase phosphoprotein 11; Zuotin-related factor 1; DnaJ homolog subfamily C member 2, N-terminally processed; DNAJC2; MPHOSPH11, MPP11, ZRF1;
Gene Name
DNAJC2
UniProt
Q99543
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein of human DNAJC2 (NP_055192.1) .
Clonality
Polyclonal
Tissue Specificity
Widely expressed.
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Dilution
WB: 1:500-1:2000
Form
Liquid
Function
Acts both as a chaperone in the cytosol and as a chromatin regulator in the nucleus. When cytosolic, acts as a molecular chaperone: component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, stimulates the ATPase activity of the ribosome-associated pool of Hsp70-type chaperones HSPA14 that bind to the nascent polypeptide chain. When nuclear, mediates the switching from polycomb- repressed genes to an active state: specifically recruited at histone H2A ubiquitinated at 'Lys-119' (H2AK119ub), and promotes the displacement of the polycomb PRC1 complex from chromatin, thereby facilitating transcription activation. Specifically binds DNA sequence 5'-GTCAAGC-3'.
Molecular Weight
71996 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.bosterbio.com/datasheet?sku=A06788
Product MSDS
https://www.bosterbio.com/msds?sku=A06788
Other Gene Names
DnaJ homolog subfamily C member 2
Subcellular Location
Nucleus
Protein Name
DnaJ homolog subfamily C member 2
Curated Selection
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