Anti-Ficolin-1 FCN1 Antibody
Boster Bio Anti-Ficolin-1 FCN1 Antibody catalog # A06751. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Ficolin-1; Collagen/fibrinogen domain-containing protein 1; Ficolin-A; Ficolin-alpha; M-ficolin; FCN1; FCNM;
Gene Name
FCN1
UniProt
O00602
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant full length Human FCN1.
Clonality
Polyclonal
Tissue Specificity
Peripheral blood leukocytes, monocytes and granulocytes. Also detected in spleen, lung, and thymus, may be due to the presence of tissue macrophages or trapped blood in these tissues. Not detected on lymphocytes.
Applications
WB, IHC
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
Extracellular lectin functioning as a pattern- recognition receptor in innate immunity. Binds the sugar moieties of pathogen-associated molecular patterns (PAMPs) displayed on microbes and activates the lectin pathway of the complement system. May also activate monocytes through a G protein-coupled receptor, FFAR2, inducing the secretion of interleukin-8/IL-8 (PubMed:21037097) . Binds preferentially to 9-O-acetylated 2-6- linked sialic acid derivatives and to various glycans containing sialic acid engaged in a 2-3 linkage.
Molecular Weight
35078 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.bosterbio.com/datasheet?sku=A06751
Product MSDS
https://www.bosterbio.com/msds?sku=A06751
Other Gene Names
Ficolin-1
Subcellular Location
Secreted
Protein Name
Ficolin-1
Curated Selection
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