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Anti-CEACAM3 Antibody

Boster Bio Anti-CEACAM3 Antibody catalog # A06613. Tested in WB applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Carcinoembryonic antigen-related cell adhesion molecule 3; Carcinoembryonic antigen CGM1; CD66d; CEACAM3; CD66D, CGM1;

Gene Name

CEACAM3

UniProt

P40198

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Recombinant fusion protein of human CD66d/CEACAM3 (NP_001806.2) .

Clonality

Polyclonal

Tissue Specificity

CGM1a, the predominant CGM1 transcript, is granulocyte-specific. Not detected out of the granulocytic lineage, such as monocytes, lymphocytes, spleen, testis, colon, brain, liver, pancreas, thymus, ovary, placenta, skeletal muscle, prostate, small intestine, heart, lung and kidney.

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Dilution

WB: 1:500-1:2000

Form

Liquid

Function

Major granulocyte receptor mediating recognition and efficient opsonin-independent phagocytosis of CEACAM-binding microorganisms, including Neissiria, Moxarella and Haemophilus species, thus playing an important role in the clearance of pathogens by the innate immune system. Responsible for RAC1 stimulation in the course of pathogen phagocytosis.

Molecular Weight

27091 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

Carcinoembryonic antigen-related cell adhesion molecule 3

Subcellular Location

Membrane; Single-pass type I membrane protein.

Protein Name

Carcinoembryonic antigen-related cell adhesion molecule 3

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