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Anti-NF-kappa-B-repressing factor NKRF Antibody

Boster Bio Anti-NF-kappa-B-repressing factor NKRF Antibody catalog # A06610. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

NF-kappa-B-repressing factor; NFkB-repressing factor; Protein ITBA4; Transcription factor NRF; NKRF; ITBA4, NRF;

Gene Name

NKRF

UniProt

O15226

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human NKRF (NP_060014.2) .

Clonality

Polyclonal

Tissue Specificity

Widely and constitutively expressed. Expressed at lower level in colon, peripheral blood lymphocytes, lung and kidney.

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Dilution

WB: 1:500-1:2000

Form

Liquid

Function

Interacts with a specific negative regulatory element (NRE) 5'-AATTCCTCTGA-3' to mediate transcriptional repression of certain NK-kappa-B responsive genes. Involved in the constitutive silencing of the interferon beta promoter, independently of the virus-induced signals, and in the inhibition of the basal and cytokine-induced iNOS promoter activity. Also involved in the regulation of IL-8 transcription.

Molecular Weight

77673 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

NF-kappa-B-repressing factor

Subcellular Location

Nucleus, nucleolus

Protein Name

NF-kappa-B-repressing factor

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