Anti-KCNJ4 Antibody

Boster Bio Anti-KCNJ4 Antibody catalog # A06605-2. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Inward rectifier potassium channel 4; HIRK2; HRK1; Hippocampal inward rectifier; HIR; Inward rectifier K (+) channel Kir2.3; IRK-3; Potassium channel, inwardly rectifying subfamily J member 4; KCNJ4; IRK3;

Gene Name

KCNJ4

UniProt

P48050

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide of human KCNJ4 (NP_004972.1) .

Clonality

Polyclonal

Tissue Specificity

Heart, skeletal muscle, and several different brain regions including the hippocampus.

Applications

WB, IHC

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Form

Liquid

Function

Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium (By similarity) . .

Molecular Weight

49500 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

Inward rectifier potassium channel 4

Subcellular Location

Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane ; Multi-pass membrane protein . Cytoplasmic vesicle membrane . TAX1BP3 binding promotes dissociation of KCNJ4 from LIN7 famaly members and KCNJ4 internalization. .