Anti-Plexin A1 PLXNA1 Antibody

Boster Bio Anti-Plexin A1 PLXNA1 Antibody catalog # A06377. Tested in WB, ICC, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Plexin-A1; Semaphorin receptor NOV; PLXNA1; NOV, PLXN1;

Gene Name

PLXNA1

UniProt

Q9UIW2

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein

Clonality

Polyclonal

Tissue Specificity

Detected in fetal brain, lung, liver and kidney.

Applications

WB, ICC, Flow Cytometry

Purification

ProA affinity purified

Form

Liquid

Function

Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down- stream signaling events in the cytoplasm (By similarity) . .