Anti-Ubiquitin-protein ligase E3C UBE3C Antibody
Boster Bio Anti-Ubiquitin-protein ligase E3C UBE3C Antibody catalog # A06324-1. Tested in WB, IHC, IF applications. This antibody reacts with Human.
Product Specifications
Synonyms
Ubiquitin-protein ligase E3C;2.3.2.26; HECT-type ubiquitin transferase E3C; HectH2; UBE3C; KIAA0010, KIAA10;
Gene Name
UBE3C
UniProt
Q15386
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant full length Human UBE3C.
Clonality
Polyclonal
Tissue Specificity
Highly expressed in skeletal muscle. Detected at much lower levels in kidney and pancreas.
Applications
WB, IHC, IF
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Can assemble unanchored poly-ubiquitin chains in either 'Lys-29'- or 'Lys-48'-linked polyubiquitin chains. Has preference for 'Lys-48' linkages. It can target itself for ubiquitination in vitro and may promote its own degradation in vivo.
Molecular Weight
123923 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Ubiquitin-protein ligase E3C
Subcellular Location
Nucleus .
Protein Name
Ubiquitin-protein ligase E3C
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