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Anti-IL-22R Alpha 2 IL22RA2 Antibody

Boster Bio Anti-IL-22R Alpha 2 IL22RA2 Antibody catalog # A06250. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Interleukin-22 receptor subunit alpha-2; IL-22 receptor subunit alpha-2; IL-22R-alpha-2; IL-22RA2; Cytokine receptor class-II member 10; Cytokine receptor family 2 member 10; CRF2-10; Cytokine receptor family type 2, soluble 1; CRF2-S1; Interleukin-22-binding protein; IL-22BP; IL22BP; ZcytoR16; IL22RA2; UNQ5793/PRO19598/PRO19822;

Gene Name

IL22RA2

UniProt

Q969J5

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide corresponding to residues in Human IL-22Rα2.

Clonality

Polyclonal

Tissue Specificity

Expressed in placenta, spleen, breast, skin and lung. Also detected in intestinal tract, testis, brain, heart and thymus. No expression found in prostate, bladder, kidney, ovary, muscle, bone marrow, liver and uterus. Isoform 1 is expressed only in placenta. Isoform 2 is expressed in placenta and breast and at lower level in spleen, skin, thymus and stomach.

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Dilution

WB: 1:500-1:1000

Form

Liquid

Function

Isoform 2 is a receptor for IL22. Binds to IL22, prevents interaction with the functional IL-22R complex and blocks the activity of IL22 (in vitro) . May play an important role as an IL22 antagonist in the regulation of inflammatory responses.

Molecular Weight

30550 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

Interleukin-22 receptor subunit alpha-2

Subcellular Location

Secreted

Protein Name

Interleukin-22 receptor subunit alpha-2

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