Anti-LRSAM1 Antibody
Boster Bio Anti-LRSAM1 Antibody catalog # A06223. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
E3 ubiquitin-protein ligase LRSAM1 ;2.3.2.27
Gene Name
LRSAM1
UniProt
Q6UWE0
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human LRSAM1 (NP_612370.3) .
Clonality
Polyclonal
Tissue Specificity
Highly expressed in adult spinal cord motoneurons as well as in fetal spinal cord and muscle tissue.
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Dilution
WB: 1:500-1:2000
Form
Liquid
Function
E3 ubiquitin-protein ligase that mediates monoubiquitination of TSG101 at multiple sites, leading to inactivate the ability of TSG101 to sort endocytic (EGF receptors) and exocytic (HIV-1 viral proteins) cargos (PubMed:15256501) . Bacterial recognition protein that defends the cytoplasm from invasive pathogens (PubMed:23245322) . Localizes to several intracellular bacterial pathogens and generates the bacteria- associated ubiquitin signal leading to autophagy-mediated intracellular bacteria degradation (xenophagy) (PubMed:23245322, PubMed:25484098) .
Molecular Weight
83594 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
E3 ubiquitin-protein ligase LRSAM1
Subcellular Location
Cytoplasm
Protein Name
E3 ubiquitin-protein ligase LRSAM1
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