Anti-F-box/LRR-repeat protein 5 FBXL5 Antibody
Boster Bio Anti-F-box/LRR-repeat protein 5 FBXL5 Antibody catalog # A06215. Tested in WB, ELISA applications. This antibody reacts with Human.
Product Specifications
Synonyms
F-box/LRR-repeat protein 5; F-box and leucine-rich repeat protein 5; F-box protein FBL4/FBL5; p45SKP2-like protein; FBXL5; FBL4, FBL5, FLR1;
Gene Name
FBXL5
UniProt
Q9UKA1
Host
Rabbit
Reactivity
Human
Immunogen
KLH conjugated synthetic peptide derived from human FBXL5: 31-130/691
Clonality
Polyclonal
Applications
WB, ELISA
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in iron homeostasis by promoting the ubiquitination and subsequent degradation of IREB2/IRP2. Upon high iron and oxygen level, it specifically recognizes and binds IREB2/IRP2, promoting its ubiquitination and degradation by the proteasome. Promotes ubiquitination and subsequent degradation of DCTN1/p150-glued.
Molecular Weight
78555 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
F-box/LRR-repeat protein 5
Subcellular Location
Cytoplasm, perinuclear region
Protein Name
F-box/LRR-repeat protein 5
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