Anti-ARAP1 Antibody

Boster Bio Anti-ARAP1 Antibody catalog # A06167. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1; Centaurin-delta-2; Cnt-d2; ARAP1; CENTD2, KIAA0782;

Gene Name

ARAP1

UniProt

Q96P48

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human ARAP1 (NP_001128662.1) .

Clonality

Polyclonal

Tissue Specificity

Detected in heart, skeletal muscle, spleen, kidney, liver, placenta, lung, peripheral blood leukocytes, adrenal gland, bone marrow, brain, lymph node, mammary gland, prostate, spinal cord, stomach, thyroid and trachea.

Applications

WB, ICC, IF

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Form

Liquid

Function

Phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol 3,4,5-trisphosphate (PtdIns (3,4,5) P3) binding. Can be activated by phosphatidylinositol 3,4-bisphosphate (PtdIns (3,4,5) P2) binding, albeit with lower efficiency. Has a preference for ARF1 and ARF5 (By similarity) .

Molecular Weight

162192 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1

Subcellular Location

Cytoplasm. Golgi apparatus, Golgi stack membrane; Peripheral membrane protein. Cell membrane. Associated with Golgi stacks in resting cells. Throughout the cytoplasm and in surface protrusion in cells that are in the process of attaching to a surface and spreading.