Anti-TNF-IP 1 (S122) TNFAIP1 Antibody
Boster Bio Anti-TNF-IP 1 (S122) TNFAIP1 Antibody catalog # A06143S122. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2; hBACURD2; BTB/POZ domain-containing protein TNFAIP1; Protein B12; Tumor necrosis factor, alpha-induced protein 1, endothelial; TNFAIP1; BACURD2, EDP1;
Gene Name
TNFAIP1
UniProt
Q13829
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 90-140 of Human TNF-IP 1.
Clonality
Polyclonal
Applications
WB, IHC
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR (TNFAIP1) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis. May enhance the PCNA-dependent DNA polymerase delta activity.
Molecular Weight
36204 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2
Subcellular Location
Cytoplasm. Nucleus. Endosome. Colocalizes with RHOB in endosomes.
Protein Name
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2
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