Anti-DGUOK Antibody
Boster Bio Anti-DGUOK Antibody catalog # A06092. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Deoxyguanosine kinase, mitochondrial; dGK;2.7.1.113; DGUOK; DGK;
Gene Name
DGUOK
UniProt
Q16854
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human DGUOK (NP_550438.1) .
Clonality
Polyclonal
Tissue Specificity
Ubiquitous. Highest expression in muscle, brain, liver and lymphoid tissues.
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Dilution
WB: 1:500-1:2000
Form
Liquid
Function
Phosphorylates deoxyguanosine and deoxyadenosine in the mitochondrial matrix, with the highest efficiency for deoxyguanosine. In non-replicating cells, where cytosolic dNTP synthesis is down-regulated, mtDNA synthesis depends solely on DGUOK and TK2. Phosphorylates certain nucleoside analogs. Widely used as target of antiviral and chemotherapeutic agents.
Molecular Weight
32056 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Deoxyguanosine kinase, mitochondrial
Subcellular Location
Mitochondrion.
Protein Name
Deoxyguanosine kinase, mitochondrial
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