Anti-SMG7 (K548) Antibody
Boster Bio Anti-SMG7 (K548) Antibody catalog # A06078-1. Tested in WB, IHC applications. This antibody reacts with Human.
Product Specifications
Synonyms
Protein SMG7; EST1-like protein C; SMG-7 homolog; hSMG-7; SMG7; C1orf16, EST1C, KIAA0250;
Gene Name
SMG7
UniProt
Q92540
Host
Rabbit
Reactivity
Human
Immunogen
Synthetic peptide, corresponding to amino acids 512-564 of Human SMG7.
Clonality
Polyclonal
Applications
WB, IHC
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
Plays a role in nonsense-mediated mRNA decay. Recruits UPF1 to cytoplasmic mRNA decay bodies. Together with SMG5 is thought to provide a link to the mRNA degradation machinery involving exonucleolytic pathways, and to serve as an adapter for UPF1 to protein phosphatase 2A (PP2A), thereby triggering UPF1 dephosphorylation.
Molecular Weight
127282 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Protein SMG7
Subcellular Location
Cytoplasm. Nucleus. Predominantly cytoplasmic, and nuclear. Shuttles between nucleus and cytoplasm.
Protein Name
Protein SMG7
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