Anti-Serglycin SRGN Antibody
Boster Bio Anti-Serglycin SRGN Antibody catalog # A06069. Tested in WB applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
Serglycin; Hematopoietic proteoglycan core protein; Platelet proteoglycan core protein; P.PG; Secretory granule proteoglycan core protein; SRGN; PRG, PRG1;
Gene Name
SRGN
UniProt
P10124
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein of human SRGN (NP_002718.2) .
Clonality
Polyclonal
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Dilution
WB: 1:500-1:2000
Form
Liquid
Function
Plays a role in formation of mast cell secretory granules and mediates storage of various compounds in secretory vesicles. Required for storage of some proteases in both connective tissue and mucosal mast cells and for storage of granzyme B in T-lymphocytes. Plays a role in localizing neutrophil elastase in azurophil granules of neutrophils. Mediates processing of MMP2. Plays a role in cytotoxic cell granule-mediated apoptosis by forming a complex with granzyme B which is delivered to cells by perforin to induce apoptosis. Regulates the secretion of TNF- alpha and may also regulate protease secretion. Inhibits bone mineralization.
Molecular Weight
17652 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Serglycin
Subcellular Location
Cytoplasmic granule
Protein Name
Serglycin
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