Anti-EIF4E2 Antibody
Boster Bio Anti-EIF4E2 Antibody catalog # A05869. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Eukaryotic translation initiation factor 4E type 2; eIF-4E type 2; eIF4E type 2; Eukaryotic translation initiation factor 4E homologous protein; Eukaryotic translation initiation factor 4E-like 3; eIF4E-like protein 4E-LP; mRNA cap-binding protein 4EHP; h4EHP
Gene Name
EIF4E2
UniProt
O60573
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human EIF4E2 (NP_004837.1) .
Clonality
Polyclonal
Applications
WB, IHC, ICC, IF
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation (PubMed:9582349, PubMed:17368478, PubMed:25624349) . Acts as a repressor of translation initiation (PubMed:22751931) . In contrast to EIF4E, it is unable to bind eIF4G (EIF4G1, EIF4G2 or EIF4G3), suggesting that it acts by competing with EIF4E and block assembly of eIF4F at the cap (By similarity) .
Molecular Weight
28362 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Eukaryotic translation initiation factor 4E type 2
Protein Name
Eukaryotic translation initiation factor 4E type 2
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