Anti-Plexin-A2 PLXNA2 Antibody
Boster Bio Anti-Plexin-A2 PLXNA2 Antibody catalog # A05706. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Plexin-A2; Semaphorin receptor OCT; PLXNA2; KIAA0463, OCT, PLXN2; UNQ209/PRO235;
Gene Name
PLXNA2
UniProt
O75051
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to residues in Human PLXNA2.
Clonality
Polyclonal
Tissue Specificity
Detected in fetal brain.
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Dilution
WB: 1:500-1:1000
Form
Liquid
Function
Coreceptor for SEMA3A and SEMA6A. Necessary for signaling by SEMA6A and class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down- stream signaling events in the cytoplasm (By similarity) .
Molecular Weight
211104 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Plexin-A2
Subcellular Location
Cell membrane ; Single-pass type I membrane protein .
Protein Name
Plexin-A2
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