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Anti-eIF5A2 (Y127) Antibody

Boster Bio Anti-eIF5A2 (Y127) Antibody catalog # A05688Y127. Tested in WB, IHC applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Eukaryotic translation initiation factor 5A-2; eIF-5A-2; eIF-5A2; Eukaryotic initiation factor 5A isoform 2; EIF5A2;

Gene Name

EIF5A2

UniProt

Q9GZV4

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Synthetic peptide, corresponding to amino acids 96-140 of Human eIF5A2.

Clonality

Polyclonal

Tissue Specificity

Expressed in ovarian and colorectal cancer cell lines (at protein level) . Highly expressed in testis. Overexpressed in some cancer cells.

Applications

WB, IHC

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Form

Liquid

Function

MRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation (By similarity) .

Molecular Weight

16793 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

Eukaryotic translation initiation factor 5A-2

Subcellular Location

Cytoplasm . Nucleus . Endoplasmic reticulum membrane ; Peripheral membrane protein ; Cytoplasmic side . Nucleus, nuclear pore complex . Hypusine modification promotes the nuclear export and cytoplasmic localization and there was a dynamic shift in the localization from predominantly cytoplasmic to primarily nuclear under apoptotic inducing conditions. .

Protein Name

Eukaryotic translation initiation factor 5A-2

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