Anti-SNRPB Antibody
Boster Bio Anti-SNRPB Antibody catalog # A05674. Tested in WB, IHC applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
Small nuclear ribonucleoprotein-associated proteins B and B'; snRNP-B; Sm protein B/B'; Sm-B/B'; SmB/B'; SNRPB; COD, SNRPB1;
Gene Name
SNRPB
UniProt
P14678
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant full length Human SNRPB.
Clonality
Polyclonal
Applications
WB, IHC
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
Plays role in pre-mRNA splicing as core component of the SMN-Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (PubMed:11991638, PubMed:18984161, PubMed:19325628, PubMed:25555158, PubMed:26912367, PubMed:28502770, PubMed:28781166, PubMed:28076346) . Component of both the pre- catalytic spliceosome B complex and activated spliceosome C complexes (PubMed:11991638, PubMed:28502770, PubMed:28781166, PubMed:28076346) . Is also a component of the minor U12 spliceosome (PubMed:15146077) . As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing (PubMed:12975319) .
Molecular Weight
24610 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Small nuclear ribonucleoprotein-associated proteins B and B'
Subcellular Location
Cytoplasm, cytosol
Protein Name
Small nuclear ribonucleoprotein-associated proteins B and B'
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