What is the catalog number for Anti-CDC42BPA Antibody?

The catalog number for Anti-CDC42BPA Antibody is A05509.

What sizes are available for Anti-CDC42BPA Antibody?

Anti-CDC42BPA Antibody is available in the following size(s): 100 µL.

Is Anti-CDC42BPA Antibody in stock?

Anti-CDC42BPA Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-CDC42BPA Antibody?

The safety data sheet for Anti-CDC42BPA Antibody is available here: https://www.bosterbio.com/msds?sku=A05509.

Anti-CDC42BPA Antibody

Boster Bio Anti-CDC42BPA Antibody catalog # A05509. Tested in WB applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Serine/threonine-protein kinase MRCK alpha;2.7.11.1; CDC42-binding protein kinase alpha; DMPK-like alpha; Myotonic dystrophy kinase-related CDC42-binding kinase alpha; MRCK alpha; Myotonic dystrophy protein kinase-like alpha; CDC42BPA

Gene Name

CDC42BPA

UniProt

Q5VT25

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A synthetic peptide corresponding to residues in Human CDC42BPA.

Clonality

Polyclonal

Tissue Specificity

Abundant in the heart, brain, skeletal muscle, kidney, and pancreas, with little or no expression in the lung and liver.

Applications

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Dilution

WB: 1:500-1:1000

Form

Liquid

Function

Serine/threonine-protein kinase which is an important downstream effector of CDC42 and plays a role in the regulation of cytoskeleton reorganization and cell migration (PubMed:15723050, PubMed:9418861, PubMed:9092543) . Regulates actin cytoskeletal reorganization via phosphorylation of PPP1R12C and MYL9/MLC2 (PubMed:21457715) . In concert with MYO18A and LURAP1, is involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration (PubMed:18854160) . Phosphorylates: PPP1R12A, LIMK1 and LIMK2 (PubMed:11340065, PubMed:11399775) . May play a role in TFRC-mediated iron uptake (PubMed:20188707) . In concert with FAM89B/LRAP25 mediates the targeting of LIMK1 to the lamellipodium resulting in its activation and subsequent phosphorylation of CFL1 which is important for lamellipodial F-actin regulation (By similarity) .