Anti-Adrenodoxin, mitochondrial FDX1 Antibody
Boster Bio Anti-Adrenodoxin, mitochondrial FDX1 Antibody catalog # A05441. Tested in WB applications. This antibody reacts with Human.
Product Specifications
Synonyms
Adrenodoxin, mitochondrial; Adrenal ferredoxin; Ferredoxin-1; Hepatoredoxin; FDX1; ADX;
Gene Name
FDX1
UniProt
P10109
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant fusion protein of human FDX1/ADX (NP_004100.1) .
Clonality
Polyclonal
Tissue Specificity
Highest levels in the adrenal gland (at protein level) . Also detected in kidney and testis (at protein level) .
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Dilution
WB: 1:500-1:2000
Form
Liquid
Function
Essential for the synthesis of various steroid hormones (PubMed:20547883, PubMed:21636783) . Participates in the reduction of mitochondrial cytochrome P450 for steroidogenesis (PubMed:20547883, PubMed:21636783) . Transfers electrons from adrenodoxin reductase to CYP11A1, a cytochrome P450 that catalyzes cholesterol side-chain cleavage (PubMed:20547883, PubMed:21636783) . Does not form a ternary complex with adrenodoxin reductase and CYP11A1 but shuttles between the two enzymes to transfer electrons (By similarity) .
Molecular Weight
19393 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Adrenodoxin, mitochondrial
Subcellular Location
Mitochondrion matrix
Protein Name
Adrenodoxin, mitochondrial
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