Anti-LTBP3 Antibody
Boster Bio Anti-LTBP3 Antibody catalog # A05426. Tested in WB applications. This antibody reacts with Human.
Product Specifications
Synonyms
Latent-transforming growth factor beta-binding protein 3; LTBP-3; LTBP3;
Gene Name
LTBP3
UniProt
Q9NS15
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant protein of human LTBP3
Clonality
Polyclonal
Tissue Specificity
Isoform 2: Expressed prominently in heart, skeletal muscle, prostate, testis, small intestine and ovary (PubMed:12154076) . Isoform 1: Strongly expressed in pancreas and liver (PubMed:12154076) .
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Dilution
WB: 1:500-1:2000
Form
Liquid
Function
Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space. Associates specifically via disulfide bonds with the Latency- associated peptide (LAP), which is the regulatory chain of TGF- beta, and regulates integrin-dependent activation of TGF-beta.
Molecular Weight
139359 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Latent-transforming growth factor beta-binding protein 3
Subcellular Location
Secreted
Protein Name
Latent-transforming growth factor beta-binding protein 3
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