Anti-Protein unc-13 homolog B UNC13B Antibody
Boster Bio Anti-Protein unc-13 homolog B UNC13B Antibody catalog # A05240. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
Protein unc-13 homolog B; Munc13-2; munc13; UNC13B; UNC13;
Gene Name
UNC13B
UniProt
O14795
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein of human UNC13B (NP_006368.3) .
Clonality
Polyclonal
Tissue Specificity
Expressed in kidney cortical epithelial cells and brain.
Applications
WB, IHC, ICC, IF
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
Plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. Is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity- depending refilling of readily releasable vesicle pool (RRP) . Essential for synaptic vesicle maturation in a subset of excitatory/glutamatergic but not inhibitory/GABA-mediated synapses (By similarity) . .
Molecular Weight
180679 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Protein unc-13 homolog B
Subcellular Location
Cytoplasm . Membrane ; Peripheral membrane protein . Cell membrane . Cell junction, synapse . Localized to synapses. Translocated to the plasma membrane in response to phorbol ester binding (By similarity) . .
Protein Name
Protein unc-13 homolog B
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