Anti-Calsequestrin 1 CASQ1 Antibody
Boster Bio Anti-Calsequestrin 1 CASQ1 Antibody catalog # A05235. Tested in WB, IHC, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Calsequestrin-1; Calmitine
Gene Name
CASQ1
UniProt
P31415
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein
Clonality
Polyclonal
Tissue Specificity
Expressed in myoblasts (at protein level) .
Applications
WB, IHC, Flow Cytometry
Purification
ProA affinity purified
Form
Liquid
Function
Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle (PubMed:28895244) . Calcium ions are bound by clusters of acidic residues at the protein surface, often at the interface between subunits. Can bind around 80 Ca (2+) ions (PubMed:28895244) . Regulates the release of lumenal Ca (2+) via the calcium release channel RYR1; this plays an important role in triggering muscle contraction. Negatively regulates store-operated Ca (2+) entry (SOCE) activity (PubMed:27185316) .
Molecular Weight
45160 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.bosterbio.com/datasheet?sku=A05235
Product MSDS
https://www.bosterbio.com/msds?sku=A05235
Other Gene Names
Calsequestrin-1
Subcellular Location
Endoplasmic reticulum
Protein Name
Calsequestrin-1
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