Anti-TNF Alpha-IP8 TNFAIP8 Antibody
Boster Bio Anti-TNF Alpha-IP8 TNFAIP8 Antibody catalog # A05158-1. Tested in WB, IF applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Tumor necrosis factor alpha-induced protein 8; TNF alpha-induced protein 8; Head and neck tumor and metastasis-related protein; MDC-3.13; NF-kappa-B-inducible DED-containing protein; NDED; SCC-S2; TNF-induced protein GG2-1; TNFAIP8;
Gene Name
TNFAIP8
UniProt
O95379
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 71-116 of Human TNFα-IP83.
Clonality
Polyclonal
Tissue Specificity
Expressed at high levels in the spleen, lymph node, thymus, thyroid, bone marrow and placenta. Expressed at high levels both in various tumor tissues, unstimulated and cytokine- activated cultured cells. Expressed at low levels in the spinal cord, ovary, lung, adrenal glands, heart, brain, testis and skeletal muscle.
Applications
WB, IF
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.
Molecular Weight
23003 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Tumor necrosis factor alpha-induced protein 8
Subcellular Location
Cytoplasm
Protein Name
Tumor necrosis factor alpha-induced protein 8
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