Anti-Fanconi anemia group I protein FANCI Antibody
Boster Bio Anti-Fanconi anemia group I protein FANCI Antibody catalog # A05108. Tested in WB applications. This antibody reacts with Human.
Product Specifications
Synonyms
Fanconi anemia group I protein; Protein FACI; FANCI; KIAA1794;
Gene Name
FANCI
UniProt
Q9NVI1
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant fusion protein of human FANCI (NP_001106849.1) .
Clonality
Polyclonal
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Dilution
WB: 1:500-1:2000
Form
Liquid
Function
Plays an essential role in the repair of DNA double- strand breaks by homologous recombination and in the repair of interstrand DNA cross-links (ICLs) by promoting FANCD2 monoubiquitination by FANCL and participating in recruitment to DNA repair sites. Required for maintenance of chromosomal stability. Specifically binds branched DNA: binds both single- stranded DNA (ssDNA) and double-stranded DNA (dsDNA) . Participates in S phase and G2 phase checkpoint activation upon DNA damage.
Molecular Weight
149324 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Fanconi anemia group I protein
Subcellular Location
Nucleus
Protein Name
Fanconi anemia group I protein
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