Anti-Adducin Beta (E497) ADD2 Antibody
Boster Bio Anti-Adducin Beta (E497) ADD2 Antibody catalog # A05106-1. Tested in WB, IHC, IF applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Beta-adducin; Erythrocyte adducin subunit beta; ADD2; ADDB;
Gene Name
ADD2
UniProt
P35612
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 470-520 of Human Adducin β.
Clonality
Polyclonal
Tissue Specificity
Expressed mainly in brain, spleen, kidney cortex and medulla, and heart. Also expressed in human umbilical vein endothelial cells, human vascular smooth muscle cells, kidney tubular cells and K-562 cell line.
Applications
WB, IHC, IF
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to the erythrocyte membrane receptor SLC2A1/GLUT1 and may therefore provide a link between the spectrin cytoskeleton to the plasma membrane. Binds to calmodulin. Calmodulin binds preferentially to the beta subunit.
Molecular Weight
80854 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Beta-adducin
Subcellular Location
Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein Name
Beta-adducin
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