Anti-AFG3-like protein 2 AFG3L2 Antibody
Boster Bio Anti-AFG3-like protein 2 AFG3L2 Antibody catalog # A04820. Tested in WB, IHC, IP applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
AFG3-like protein 2;3.4.24.-
Gene Name
AFG3L2
UniProt
Q9Y4W6
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human AFG3L2 (NP_006787.2) .
Clonality
Polyclonal
Tissue Specificity
Ubiquitous. Highly expressed in the cerebellar Purkinje cells.
Applications
WB, IHC, IP
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
ATP-dependent protease which is essential for axonal and neuron development. In neurons, mediates degradation of SMDT1/EMRE before its assembly with the uniporter complex, limiting the availability of SMDT1/EMRE for MCU assembly and promoting efficient assembly of gatekeeper subunits with MCU (PubMed:27642048) . Required for the maturation of paraplegin (SPG7) after its cleavage by mitochondrial-processing peptidase (MPP), converting it into a proteolytically active mature form (By similarity) .
Molecular Weight
88584 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.bosterbio.com/datasheet?sku=A04820
Product MSDS
https://www.bosterbio.com/msds?sku=A04820
Other Gene Names
AFG3-like protein 2
Subcellular Location
Mitochondrion
Protein Name
AFG3-like protein 2
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