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Anti-AFG3-like protein 2 AFG3L2 Antibody

Boster Bio Anti-AFG3-like protein 2 AFG3L2 Antibody catalog # A04820. Tested in WB, IHC, IP applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

AFG3-like protein 2;3.4.24.-

Gene Name

AFG3L2

UniProt

Q9Y4W6

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human AFG3L2 (NP_006787.2) .

Clonality

Polyclonal

Tissue Specificity

Ubiquitous. Highly expressed in the cerebellar Purkinje cells.

Applications

WB, IHC, IP

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Form

Liquid

Function

ATP-dependent protease which is essential for axonal and neuron development. In neurons, mediates degradation of SMDT1/EMRE before its assembly with the uniporter complex, limiting the availability of SMDT1/EMRE for MCU assembly and promoting efficient assembly of gatekeeper subunits with MCU (PubMed:27642048) . Required for the maturation of paraplegin (SPG7) after its cleavage by mitochondrial-processing peptidase (MPP), converting it into a proteolytically active mature form (By similarity) .

Molecular Weight

88584 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

AFG3-like protein 2

Subcellular Location

Mitochondrion

Protein Name

AFG3-like protein 2

Frequently Asked Questions

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