Anti-Hairless (E77) HR Antibody
Boster Bio Anti-Hairless (E77) HR Antibody catalog # A04817-2. Tested in IHC applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Lysine-specific demethylase hairless;1.14.11.-; HR;
Gene Name
HR
UniProt
O43593
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 51-100 of Human Hairless.
Clonality
Polyclonal
Tissue Specificity
Strongest expression of isoforms 1 and 2 is seen in the small intestine, weaker expression in brain and colon, and trace expression is found in liver, pancreas, spleen, thymus, stomach, salivary gland, appendix and trachea. Isoform 1 is always the most abundant. Isoform 1 is exclusively expressed at low levels in kidney and testis. Isoform 2 is exclusively expressed at high levels in the skin.
Applications
IHC
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Dilution
IHC: 1:50-1:200
Form
Liquid
Function
Histone demethylase that specifically demethylates both mono- and dimethylated 'Lys-9' of histone H3. May act as a transcription regulator controlling hair biology (via targeting of collagens), neural activity, and cell cycle.
Molecular Weight
127495 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Lysine-specific demethylase hairless
Subcellular Location
Nucleus.
Protein Name
Lysine-specific demethylase hairless
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