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Anti-PRMT2 Antibody

Boster Bio Anti-PRMT2 Antibody catalog # A04706. Tested in WB, IHC, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Protein arginine N-methyltransferase 2;2.1.1.319

Gene Name

PRMT2

UniProt

P55345

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant full length Human PRMT2.

Clonality

Polyclonal

Tissue Specificity

Widely expressed. Highly expressed in androgen target organs such as heart, prostate, skeletal muscle, ovary and spinal cord.

Applications

WB, IHC, IF

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Form

Liquid

Function

Arginine methyltransferase that methylates the guanidino nitrogens of arginyl residues in proteins such as STAT3, FBL, histone H4. Acts as a coactivator (with NCOA2) of the androgen receptor (AR) -mediated transactivation. Acts as a coactivator (with estrogen) of estrogen receptor (ER) -mediated transactivation. Enhances PGR, PPARG, RARA-mediated transactivation. May inhibit NF-kappa-B transcription and promote apoptosis. Represses E2F1 transcriptional activity (in a RB1- dependent manner) . May be involved in growth regulation.

Molecular Weight

49042 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

Protein arginine N-methyltransferase 2

Subcellular Location

Isoform 1: Cytoplasm. Nucleus. Translocates from the cytoplasm to the nucleus, after hormone exposure. Excluded from nucleolus.

Protein Name

Protein arginine N-methyltransferase 2

Frequently Asked Questions

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