Anti-GPSM2 Antibody
Boster Bio Anti-GPSM2 Antibody catalog # A04699. Tested in WB applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
G-protein-signaling modulator 2; Mosaic protein LGN
Gene Name
GPSM2
UniProt
P81274
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein of human GPSM2 (NP_037428.3) .
Clonality
Polyclonal
Tissue Specificity
Ubiquitously expressed.
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Dilution
WB: 1:1000-1:2000
Form
Liquid
Function
Plays an important role in mitotic spindle pole organization via its interaction with NUMA1 (PubMed:11781568, PubMed:15632202, PubMed:21816348) . Required for cortical dynein- dynactin complex recruitment during metaphase (PubMed:22327364) . Plays a role in metaphase spindle orientation (PubMed:22327364) . Plays also an important role in asymmetric cell divisions (PubMed:21816348) . Has guanine nucleotide dissociation inhibitor (GDI) activity towards G (i) alpha proteins, such as GNAI1 and GNAI3, and thereby regulates their activity (By similarity) .
Molecular Weight
76662 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
G-protein-signaling modulator 2
Subcellular Location
Cytoplasm
Protein Name
G-protein-signaling modulator 2
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