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Anti-G Alpha t1 (M104) GNAT1 Antibody

Boster Bio Anti-G Alpha t1 (M104) GNAT1 Antibody catalog # A04598t1. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Guanine nucleotide-binding protein G (t) subunit alpha-1; Transducin alpha-1 chain; GNAT1; GNATR;

Gene Name

GNAT1

UniProt

P11488

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 71-120 of Human Gα t1.

Clonality

Polyclonal

Tissue Specificity

Rod photoreceptor cells (PubMed:1614872) . Predominantly expressed in the retina followed by the ciliary body, iris and retinal pigment epithelium (PubMed:22190596) .

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Dilution

WB: 1:500-1:1000

Form

Liquid

Function

Functions as signal transducer for the rod photoreceptor RHO. Required for normal RHO-mediated light perception by the retina (PubMed:22190596) . Guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs), such as the photoreceptor RHO. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Activated RHO promotes GDP release and GTP binding. Signaling is mediated via downstream effector proteins, such as cGMP-phosphodiesterase (By similarity) .

Molecular Weight

40041 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A04598t1

Product MSDS

https://www.bosterbio.com/msds?sku=A04598t1

Other Gene Names

Guanine nucleotide-binding protein G (t) subunit alpha-1

Subcellular Location

Cell projection, cilium, photoreceptor outer segment

Protein Name

Guanine nucleotide-binding protein G (t) subunit alpha-1

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