Anti-LETM1 Antibody

Boster Bio Anti-LETM1 Antibody catalog # A04547. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Mitochondrial proton/calcium exchanger protein ; Leucine zipper-EF-hand-containing transmembrane protein 1; LETM1

Gene Name

LETM1

UniProt

O95202

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human LETM1 (NP_036450.1) .

Clonality

Polyclonal

Applications

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Dilution

WB: 1:500-1:2000

Form

Liquid

Function

Mitochondrial proton/calcium antiporter that mediates proton-dependent calcium efflux from mitochondrion (PubMed:19797662) . Crucial for the maintenance of mitochondrial tubular networks and for the assembly of the supercomplexes of the respiratory chain (PubMed:18628306) . Required for the maintenance of the tubular shape and cristae organization (PubMed:18628306) . In contrast to SLC8B1/NCLX, does not constitute the major factor for mitochondrial calcium extrusion (PubMed:24898248) .