Anti-Oct-2 (H3) POU2F2 Antibody
Boster Bio Anti-Oct-2 (H3) POU2F2 Antibody catalog # A04407-1. Tested in WB, IHC, IF applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
POU domain, class 2, transcription factor 2; Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2; Octamer-binding protein 2; Oct-2; Octamer-binding transcription factor 2; OTF-2; POU2F2; OCT2, OTF2;
Gene Name
POU2F2
UniProt
P09086
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthetic peptide, corresponding to the N-terminus of Human Oct-2.
Clonality
Polyclonal
Tissue Specificity
Isoform 3 is B-cell specific. Isoform 5 is expressed in B-cells and the immunoglobulin-expressing T-cell line MOLT-4, but not in the T-cell line BW5147.
Applications
WB, IHC, IF
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3') . Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform 5 activates the U2 small nuclear RNA (snRNA) promoter.
Molecular Weight
51209 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
POU domain, class 2, transcription factor 2
Subcellular Location
Cytoplasm . Nucleus.
Protein Name
POU domain, class 2, transcription factor 2
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