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Anti-TLE4 (H190) Antibody

Boster Bio Anti-TLE4 (H190) Antibody catalog # A04314. Tested in WB, IHC, IP applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Transducin-like enhancer protein 4; Grg-4; Groucho-related protein 4; TLE4; GRG4, KIAA1261;

Gene Name

TLE4

UniProt

Q04727

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 170-230 of Human TLE4.

Clonality

Polyclonal

Tissue Specificity

In all tissues examined, mostly in brain, and muscle.

Applications

WB, IHC, IP

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Form

Liquid

Function

Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Essential for the transcriptional repressor activity of SIX3 during retina and lens development and for SIX3 transcriptional auto-repression (By similarity) . .

Molecular Weight

83755 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

Transducin-like enhancer protein 4

Subcellular Location

Nucleus.

Protein Name

Transducin-like enhancer protein 4

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