Anti-PARD6A Antibody
Boster Bio Anti-PARD6A Antibody catalog # A04207. Tested in WB applications. This antibody reacts with Rat.
Product Specifications
Synonyms
Partitioning defective 6 homolog alpha; PAR-6; PAR-6 alpha; PAR-6A; PAR6C; Tax interaction protein 40; TIP-40; PARD6A; PAR6A;
Gene Name
PARD6A
UniProt
Q9NPB6
Host
Rabbit
Reactivity
Rat
Immunogen
Recombinant fusion protein of human PARD6A (NP_001032358.1) .
Clonality
Polyclonal
Tissue Specificity
Expressed in pancreas, skeletal muscle, brain and heart. Weakly expressed in kidney and placenta.
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Dilution
WB: 1:500-1:2000
Form
Liquid
Function
Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in the formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins (PubMed:10873802) . Regulates centrosome organization and function. Essential for the centrosomal recruitment of key proteins that control centrosomal microtubule organization (PubMed:20719959) .
Molecular Weight
37388 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Partitioning defective 6 homolog alpha
Subcellular Location
Cytoplasm. Cell membrane. Cell projection, ruffle. Cell junction, tight junction. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite
Protein Name
Partitioning defective 6 homolog alpha
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