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Anti-Transcription factor Dp-1 TFDP1 Antibody

Boster Bio Anti-Transcription factor Dp-1 TFDP1 Antibody catalog # A04204. Tested in WB, IHC, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Transcription factor Dp-1; DRTF1-polypeptide 1; DRTF1; E2F dimerization partner 1; TFDP1; DP1;

Gene Name

TFDP1

UniProt

Q14186

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant full length Human TFDP1.

Clonality

Polyclonal

Tissue Specificity

Highest levels in muscle. Also expressed in brain, placenta, liver and kidney. Lower levels in lung and pancreas. Not detected in heart.

Applications

WB, IHC, IF

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Form

Liquid

Function

Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication (PubMed:8405995, PubMed:7739537) . The E2F1:DP complex appears to mediate both cell proliferation and apoptosis. Blocks adipocyte differentiation by repressing CEBPA binding to its target gene promoters (PubMed:20176812) .

Molecular Weight

45070 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A04204

Product MSDS

https://www.bosterbio.com/msds?sku=A04204

Other Gene Names

Transcription factor Dp-1

Subcellular Location

Nucleus

Protein Name

Transcription factor Dp-1

Curated Selection

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