What is the catalog number for Anti-ERCC8 Antibody?

The catalog number for Anti-ERCC8 Antibody is A04153.

What sizes are available for Anti-ERCC8 Antibody?

Anti-ERCC8 Antibody is available in the following size(s): 100 µL.

Is Anti-ERCC8 Antibody in stock?

Anti-ERCC8 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-ERCC8 Antibody?

The safety data sheet for Anti-ERCC8 Antibody is available here: https://www.bosterbio.com/msds?sku=A04153.

Anti-ERCC8 Antibody

Boster Bio Anti-ERCC8 Antibody catalog # A04153. Tested in WB applications. This antibody reacts with Mouse.

Product Specifications

Synonyms

DNA excision repair protein ERCC-8; Cockayne syndrome WD repeat protein CSA; ERCC8; CKN1, CSA;

Gene Name

ERCC8

UniProt

Q13216

Host

Rabbit

Reactivity

Mouse

Immunogen

A synthetic peptide of human ERCC8 (NP_000073.1) .

Clonality

Polyclonal

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Dilution

WB: 1:500-1:2000

Form

Liquid

Function

Substrate-recognition component of the CSA complex, a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex, involved in transcription-coupled nucleotide excision repair. The CSA complex (DCX (ERCC8) complex) promotes the ubiquitination and subsequent proteasomal degradation of ERCC6 in a UV-dependent manner; ERCC6 degradation is essential for the recovery of RNA synthesis after transcription-coupled repair. It is required for the recruitment of XAB2, HMGN1 and TCEA1/TFIIS to a transcription- coupled repair complex which removes RNA polymerase II-blocking lesions from the transcribed strand of active genes.