Anti-TEBP (phospho-S133) PTGES3 Antibody
Boster Bio Anti-TEBP (phospho-S133) PTGES3 Antibody catalog # A04136S133. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Prostaglandin E synthase 3;5.3.99.3
Gene Name
PTGES3
UniProt
Q15185
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide derived from human TEBP around the phosphorylation site of S133.
Clonality
Polyclonal
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Dilution
WB: 1:500-1:1000
Form
Liquid
Function
Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2) (PubMed:10922363) . Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes (PubMed:11274138, PubMed:12077419) . Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway (PubMed:24711448) .
Molecular Weight
18697 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Prostaglandin E synthase 3
Subcellular Location
Cytoplasm
Protein Name
Prostaglandin E synthase 3
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