Anti-ZBTB17 Antibody
Boster Bio Anti-ZBTB17 Antibody catalog # A03938. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Zinc finger and BTB domain-containing protein 17; Myc-interacting zinc finger protein 1; Miz-1; Zinc finger protein 151; Zinc finger protein 60; ZBTB17; MIZ1, ZNF151, ZNF60;
Gene Name
ZBTB17
UniProt
Q13105
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human ZBTB17 (NP_003434.2) .
Clonality
Polyclonal
Tissue Specificity
Expressed in germinal center B-cells.
Applications
WB, IHC
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
Transcription factor that can function as an activator or repressor depending on its binding partners, and by targeting negative regulators of cell cycle progression. Plays a critical role in early lymphocyte development, where it is essential to prevent apoptosis in lymphoid precursors, allowing them to survive in response to IL7 and undergo proper lineage commitment. Has been shown to bind to the promoters of adenovirus major late protein and cyclin D1 and activate transcription. Required for early embryonic development during gastrulation. Represses RB1 transcription; this repression can be blocked by interaction with ZBTB49 isoform 3/ZNF509S1 (PubMed:25245946) .
Molecular Weight
87928 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.bosterbio.com/datasheet?sku=A03938
Product MSDS
https://www.bosterbio.com/msds?sku=A03938
Other Gene Names
Zinc finger and BTB domain-containing protein 17
Subcellular Location
Nucleus
Protein Name
Zinc finger and BTB domain-containing protein 17
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