Anti-TXNRD2 (S501) Antibody
Boster Bio Anti-TXNRD2 (S501) Antibody catalog # A03900S501. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Thioredoxin reductase 2, mitochondrial;1.8.1.9; Selenoprotein Z; SelZ; TR-beta; Thioredoxin reductase TR3; TXNRD2; KIAA1652, TRXR2;
Gene Name
TXNRD2
UniProt
Q9NNW7
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 471-520 of Human TXNRD2.
Clonality
Polyclonal
Tissue Specificity
Highly expressed in the prostate, ovary, liver, testis, uterus, colon and small intestine. Intermediate levels in brain, skeletal muscle, heart and spleen. Low levels in placenta, pancreas, thymus and peripheral blood leukocytes. According to PubMed:10608886, high levels in kidney, whereas according to PubMed:9923614, levels are low. High expression is observed in the adrenal cortex (PubMed:24601690) .
Applications
WB, IHC
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
Involved in the control of reactive oxygen species levels and the regulation of mitochondrial redox homeostasis (PubMed:24601690) . Maintains thioredoxin in a reduced state. May play a role in redox-regulated cell signaling.
Molecular Weight
56507 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Thioredoxin reductase 2, mitochondrial
Subcellular Location
Mitochondrion
Protein Name
Thioredoxin reductase 2, mitochondrial
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