Anti-HBO1 (S167) KAT7 Antibody
Boster Bio Anti-HBO1 (S167) KAT7 Antibody catalog # A03896S167. Tested in WB, IF, IP applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Histone acetyltransferase KAT7;2.3.1.48
Gene Name
KAT7
UniProt
O95251
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 141-190 of Human HBO1.
Clonality
Polyclonal
Tissue Specificity
Ubiquitously expressed, with highest levels in testis.
Applications
WB, IF, IP
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
Component of the HBO1 complex which has a histone H4- specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Involved in H3K14 (histone H3 lysine 14) acetylation and cell proliferation (By similarity) . Through chromatin acetylation it may regulate DNA replication and act as a coactivator of TP53-dependent transcription. Acts as a coactivator of the licensing factor CDT1 (PubMed:18832067) . Specifically represses AR-mediated transcription.
Molecular Weight
70642 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Histone acetyltransferase KAT7
Subcellular Location
Nucleus, nucleoplasm
Protein Name
Histone acetyltransferase KAT7
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