Anti-Claudin-7 (S204) CLDN7 Antibody
Boster Bio Anti-Claudin-7 (S204) CLDN7 Antibody catalog # A03851S204. Tested in WB, IHC applications. This antibody reacts with Human, Rat.
Product Specifications
Synonyms
Claudin-7; CLDN-7; CLDN7; CEPTRL2, CPETRL2;
Gene Name
CLDN7
UniProt
O95471
Host
Rabbit
Reactivity
Human, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 171-220 of Human Claudin-7.
Clonality
Polyclonal
Tissue Specificity
Expressed in kidney, lung and prostate. Isoform 1 seems to be predominant, except in some normal prostate samples, where isoform 2 is the major form. Down-regulated in breast cancers, including ductal carcinoma in situ (DCIS), lobular carcinoma in situ (LCIS) and invasive ductal carcinoma (IDC) (at protein level), as well as in several cancer cell lines. Loss of expression correlates with histological grade, occurring predominantly in high-grade lesions.
Applications
WB, IHC
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
Plays a major role in tight junction-specific obliteration of the intercellular space. .
Molecular Weight
22418 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Claudin-7
Subcellular Location
Cell membrane
Protein Name
Claudin-7
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