Anti-SAE2 (S621) UBA2 Antibody
Boster Bio Anti-SAE2 (S621) UBA2 Antibody catalog # A03816S621. Tested in WB, IHC, IF applications. This antibody reacts with Human.
Product Specifications
Synonyms
SUMO-activating enzyme subunit 2;2.3.2.-; Anthracycline-associated resistance ARX; Ubiquitin-like 1-activating enzyme E1B; Ubiquitin-like modifier-activating enzyme 2; UBA2; SAE2, UBLE1B; HRIHFB2115;
Gene Name
UBA2
UniProt
Q9UBT2
Host
Rabbit
Reactivity
Human
Immunogen
Synthetic peptide, corresponding to amino acids 598-640 of Human SAE2.
Clonality
Polyclonal
Applications
WB, IHC, IF
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.
Molecular Weight
71224 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
SUMO-activating enzyme subunit 2
Subcellular Location
Cytoplasm. Nucleus. Shuttles between the cytoplasm and the nucleus, sumoylation is required either for nuclear translocation or nuclear retention.
Protein Name
SUMO-activating enzyme subunit 2
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