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Anti-SR-4 (D47) HTR4 Antibody

Boster Bio Anti-SR-4 (D47) HTR4 Antibody catalog # A03681-3. Tested in WB, IHC, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

5-hydroxytryptamine receptor 4;5-HT-4;5-HT4; Serotonin receptor 4; HTR4;

Gene Name

HTR4

UniProt

Q13639

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 14-66 of Human SR-4.

Clonality

Polyclonal

Tissue Specificity

Isoform 5-HT4 (A) is expressed in ileum, brain, and atrium, but not in the ventricle.

Applications

WB, IHC, IF

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Form

Liquid

Function

This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase.

Molecular Weight

43761 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

5-hydroxytryptamine receptor 4

Subcellular Location

Cell membrane; Multi-pass membrane protein. Endosome. Interaction with SNX27 mediates recruitment to early endosomes, while interaction with SLC9A3R1 and EZR might target the protein to specialized subcellular regions, such as microvilli. .

Protein Name

5-hydroxytryptamine receptor 4

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